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The Prostate: Part I – BNP What is situated below a body of water, has four zones and is commonly associated with venial pleasures. No it is not some romantic European city, but rather a walnut sized male organ that serves important procreative functions. It also happens to be an organ that plagues men as we age. This organ or gland is the prostate. This is the first of two articles on the male prostate. This article will focus on a disease process that affects older men, something we refer to as benign prostatic hyperplasia (BPH). BPH is a non-cancerous growth in the size of the prostate gland that impairs the flow of urine out of the bladder. The second article will focus of prostate cancer. But first a little about the small yet important male organ. The gland is located just below the bladder. It usually measures one inch by one-and-a-half inches (approximately the size of a walnut). It surrounds the urethra (the tube that takes urine out of the bladder). It is responsible for producing a fluid important in male sexual function. In the past the prostate was described as having “lobes”, but today we refer to it as having concentric zones. These zones are important both on an anatomical as well as histological level. We can separate pathology along these zones as well. For instance most all cancers occur in the peripheral zone while the benign process of enlargement occurs almost exclusively in the transitional zone (which only occupies about 5% of the total prostate volume). The prostate gland is also made up of different cell types. Cancer cells develop from the epithelial cells, but it is the interaction with stromal cells that is important in the behavior of the cancer. BPH develops from an interaction between these cells as well, but it is complex and poorly understood. Testosterone and other hormones and their interactions with this gland are hot topics of research in understanding prostate disease. The prostate gland produces most of what is found in the male ejaculate. The average volume is about 3 mL. This is less than a teaspoon and only 1% of it is sperm. The majority of the semen volume is made of products of the seminal vesicles and the prostate. The male ejaculate is very rich in potassium, zinc, citric acid and fructose. Along with these substances it also contains prostaglandins. There are many other unusual substances found in the semen. Not all is know about their function or purpose. This important male organ is a complex mix of anatomical structures and cell types that make it possible for human reproduction. However beyond the reproductive years of men, this organ becomes one of burden rather than usefulness. We will discuss the finer points of BPH and how to best avoid it and if plagued with it, treatment options. BPH typically affects men from their fourth to fifth decade of life and beyond. Several hormones come into play that have a drastic effect on the transitional zone (the zone that is most central and surrounding the urethra). Namely a metabolite of the male androgen Testosterone called Dihydrotestosterone (DHT) plays a big part on the enlargement of cells of the prostate and the encroachment on the urethra. There are several signs and symptoms that correlate with BPH and they are: slow urinary flow, the urge to urinate all the time, nighttime urination, enlargement and distension of the bladder with continuous urine leakage (incontinence) and urinary obstruction. Autopsies suggest that more than 90% of men older than 70 years have BPH. The average age for symptomatic development is about 65 years for white Americans and about 60 years for African-American men. Ways to prevent the effects of DHT on the prostate gland and the ensuing enlargement are via medications that block the enzyme 5-alpha-reductase, which converts Testosterone to DHT. Proscar is such a drug commercially available through a pharmaceutical company. Proscar works on blocking the effects of androgens on the epithelial cells and can actually shrink the size of the prostate making some of the symptoms of BPH resolve. Alternatively two FDA approved drugs that aid in symptoms of BPH (but act differently than Proscar) are Hytrin and Cardura. Both Hytrin and Cardura are drugs in the alpha1-blocker class. Originally researched as a centrally acting blood pressure reducer for patient with hypertension, it was discovered that this drug would actually relax the prostate tissue surrounding the urethra making symptoms of BPH resolve. Side effects generally include low blood pressure, dizziness, and nasal stuffiness. While neither of these two drugs will “cure” or reverse the process, they certainly do provide symptom relief for the patient plagued with BPH. Another way to treat this disease and a more natural approach is the use of herbs know for their anti-androgenic effects on the prostate. These include the well-studied Saw Palmetto herbal extract that blocks 5-alpha-reductase in the same manner as the prescription drug. Saw Palmetto taken in a standardized dose of 160mg twice daily has shown increased urine flow, with minimal side effects. Saw Palmetto is an herb indigenous to the Lowcountry of Georgia and South Carolina. Pygeum Africanum is shown to do the same yet it is not as effective and there is a fair degree of stomach symptoms. Pygeum is derived from an African evergreen tree. Stinging Nettles (Radix urticae) is another herb used widely in Europe for prostate health that has been shown to lower the residual urine volume in men with enlarged prostates. These phytotherapeutics (plant derived medicines), used and described by the Egyptians as far back as the 15 Century B.C., have a common compounds called phytosterols. The most effective phytosterol is beta sito sterol for BPH. None of the medications or herbs has been shown to prevent prostate cancer. These prescription medications and herbs are for the treatment, reduction in size or prevention of the benign process of enlargement of the prostate. Prostate cancer prevention and treatment is by other means and the subject of the next article. Besides the herbal and drug therapies there are a few surgical therapies worth mentioning. These include the most common transurethral resection of the prostate or TURP. This is where under the care of an urologist the constricted urethra within the prostate gland is “reamed out” thus mechanically or surgically widened the opening. A variant of this is the transurethral incision of the prostate (TUIP) where an incision rather than resection of the tissue is performed. A suitable procedure for patients with prostates 100 mL in volume. This involves an abdominal operation and removal of the whole prostate. Of course symptoms mentioned above for TURP are of greater frequency with this more radical procedure. There is also thermotherapy (a type of microwave treatment) that alleviates irritative symptoms, but not much is available in long-term results in the medical literature. And finally stent placement is an option. This can be used in selected cases of patients with a poor general condition and in the non-operative candidate. Symptoms of BPH include: Obstructive symptoms: Hesitancy in initiating voiding (trouble getting started) Weak urinary stream, prolonged voiding Post-voiding dribbling (mild incontinence) Sensation of incomplete emptying Nocturia (night time urination) Overflow incontinence Acute urinary retention (very painful condition) Irritative symptoms: Dysuria (discomfort in urination) Frequency Urgency Scoring BPH: The American Urological Association Symptom Index (AUASI) and International Prostate Symptom Score (IPSS) are now considered the gold standard measurement tools for the assessment of BPH symptoms and response to treatment. Both questionnaires can be used by a physician in a clinical practice to quantify the subjective symptoms of BPH and monitor therapies. Part II in this series will cover annual examination of the prostate, blood testing, prostate cancer. It will also cover prevention and treatment of prostate cancer. Reference: http://www.prostatehealth.com Lowe, FC. Et al, Phytotherapy in treatment of benign prostatic hyperplasia: a critical review. Urology 48:12-19, 1996 Dreikorn, K. et al, Stellenwert von Phytotherapeutica dei der Behandulng der benighnen Prostatahyperplasia. Urologe (A)34:119-129, 1995 Fitzpatrick, J.M. et al, Phytotherapeutic Agents in Management of Symptomatic Benign Prostatic Hyperplasia. Urological Clinics of North America. 22:407-412, 1995 Wilt T, Ishani A, Mac Donald R.. Serenoa repens for benign prostatic hyperplasia. The Cochrane Database of Systematic Reviews 2002, Issue 3. Art. No.: CD001423. DOI: 10.1002/14651858.CD001423. [Research by Sagalowski and Wilson, 1998] © 2005 does penis elargement work vimax male virility sexual enhancement top rated penis enargement pills surgical penis enlargment free penis enlagement pennis enlargement penile enlargment procedure permanent penis enlargment vigrx pic
Over 20 million Americans are currently diagnosed with some form of thyroid disease, a health problem that impacts every cell in the body and can cause severe weight gain or weight loss, mood disturbances and even infertility in both men and women. While thyroid problems are most common in women, affecting approximately 1 in 8 women between the ages of 35 and 65, men are not immune to thyroid disorders. Common symptoms in men, such as reduced libido, difficulty achieving erection and breast tenderness or enlargement, may be too embarrassing for men to seek medical help and could contribute to the lower instances of thyroid disease recorded in men. The thyroid gland is located at the base of the neck directly below the Adam’s apple. This tiny little gland shaped like a butterfly is responsible for regulating the body’s metabolism which is the rate at which the body uses energy by releasing the thyroid hormone T4 (tetraiodide) into the bloodstream. T4 makes its way to every cell in the body where it is converted to T3 (triiodothyronine), a hormone that controls the rate of cellular metabolism activity. The pituitary gland works in concert with the thyroid by regulating the levels of T3 in the body. When more T3 is needed the pituitary gland sends Thyroid Stimulating Hormone (TSH) to the thyroid gland to stimulate the release of T4 into the bloodstream. When too much thyroid hormone is present the pituitary gland stops sending out TSH and the thyroid stops the production of T4. The process is a delicate balance and if either the pituitary or the thyroid gland is failing to function properly the result will be a body that is not functioning properly. When the thyroid gland becomes overactive, releasing more hormones than are necessary, the result is hyperthyroidism or Graves Disease which is an autoimmune disease that causes over-activity of the thyroid gland. Hyperthyroidism is most common between the ages of 20 and 40 and affects roughly 1 million Americans today. With hyperthyroid, everything in the body speeds up. When the rate of cellular activity increases, more calories must be consumed to maintain normal energy levels. If the incoming calories fail to be enough then weight loss will occur. Generally, the more severe the hyperthyroid, the more weight loss will result. It is not uncommon, however, for a person with hyperthyroid to gain weight if more calories than necessary are being consumed. Patients with hyperthyroidism may also experience fatigue, trouble sleeping, increased appetite, trembling hands, irregular heartbeat, irritability and reduced libido. In severe cases, muscle weakness, shortness of breath and chest pain may result. Often however, the symptoms of hyperthyroidism are mild and may occur gradually over a long period of time. Foods that naturally suppress thyroid hormone production are cruciferous vegetables, soybeans, peaches and pears. Have two servings of these foods daily. Carrots, celery, onion and almonds are also beneficial. Hypothyroidism is a far more common problem, affecting approximately 11 million Americans. The disease can affect both men and women but it is mostly diagnosed in middle-aged women. Hypothyroid is the complete opposite of hyperthyroid. In a patient with hypothyroid the entire metabolism moves at a slower speed and requires less calories than usual to maintain normal energy levels. As a result, the excess calories consumed become stored as fat and weight gain ensues. Weight gain, while the most common problem associated with hypothyroid, is not the only symptom of an underactive thyroid gland. Other symptoms include low energy levels, depression, irritability, intolerance to heat or cold, decreased heart rate, dry skin and frequent infections, along with decreased sex drive, infertility, hair loss, dry hair and shortness of breath. As with hyperthyroid, it is not uncommon to experience few to no symptoms of this disease. To combat hypothyroidism, consume foods that contain iodine such as kelp, radish, parsley, potatoes, fish, oatmeal and bananas or look for a supplement that has 150 mg of Iodine. Iodine is needed by the body to form thyroid hormone. Also, copper, iron, selenium and zinc are essential in the production of T3 and T4. Exercise 15-20 minutes per day—enough to raise the heartbeat. Diseases of the thyroid can be diagnosed with a simple blood test which evaluates levels of free T3 and free AT4 (TSH) in the bloodstream. Another way to measure is by taking and recording the basal body temperature under the arm as soon as you wake up for ten minutes, five mornings in a row. The normal axillary temperature is 97.8 – 98.2 degrees F. If the temperature averages 97.4 or less see your physician. Once a diagnosis of either hypothyroidism or hyperthyroidism has been ascertained, treatment is aimed at restoring proper levels of the thyroid hormones. With hyperthyroidism this might require surgery or the use of medication. Hypothyroid is usually treated with hormone replacement therapy. In my practice I have found that natural thyroid hormone can be a safe and very successful means of restoring the appropriate levels. For both diseases, restoring proper levels of the thyroid hormone can result in a reversal of symptoms, including a return to pre-thyroid disease weight. If you suspect that you might be suffering from a thyroid disorder, see your doctor immediately for an evaluation. 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Children and teenagers are commonly confronted with strep throat. Due to its very contagious character, strep throat can be easily acquired by children during the flu seasons. Strep throat is a type a sore throat caused by infection with group A streptococcus bacteria. Unlike sore throat, the bacterial form of the illness usually generates more intense symptoms which can persist for more than a week. Strep throat can cause symptoms such as throat inflammation and pain, enlargement of the tonsils and lymph nodes, difficult swallowing, difficult breathing, mucus-producing cough, headache, fatigue, poor appetite, nausea and fever. When it occurs in children, strep throat can also be accompanied by skin rash. The reason why strep throat is very common among children and teenagers is that they interact with large groups of persons in kindergarten or school, rendering them very vulnerable to contracting streptococcus bacteria or other infectious agents. In order to avoid the occurrence of strep throat, it is very important to timely educate your child in maintaining a good level of personal hygiene. Proper personal hygiene is a very effective means of preventing strep throat and many other types of contagious diseases. Especially in the flu seasons, teach your child to wash his hands regularly and to avoid sharing personal items with other people. Once acquired, strep throat can be very difficult to overcome and hence it is best to take proper measures in preventing the occurrence of the illness in the first place. When your child has a persistent sore throat accompanied by fever, inflamed tonsils and lymph nodes, it is a sign of infection with bacteria and you should pay a visit to a pediatrician as soon as possible. Before seeking medical guidance, avoid giving your child left-over medications, as you can generate more harm rather than good. Administered to very young children, even aspirin can have pronounced side-effects. It is very important to note that strep throat doesn’t clear on itself. Unlike most sore throats, strep throat may require a course of antibiotics. Although antibiotics have various side-effects and they also attack the body’s benign bacterial flora, in present they are the best means of curing strep throat. Prescribed in the incipient stages of infection, antibiotics such as penicillin and amoxicillin can effectively overcome strep throat, also minimizing the risk of developing complications. If the infection is serious, the doctor may prescribe a course of cephalosporins, a strong type of antibiotics. In order to ensure a complete recovery and to avoid a recurrence of the infection, the medical treatment with antibiotics needs to be administered for at least 10 days. It is very important to follow the doctor’s exact instructions when giving antibiotics to your child. Make sure that you respect the dosage specified by the doctor and avoid interrupting the treatment prematurely. Even if the child appears to be completely recovered from illness within the first days of treatment, it is important to complete the course of antibiotics in order to minimize the chances of relapse. magna rx pills vimax does penis enlargement work penile enlargment surgery picture permanent penis enlarement top rated penis enlargement pill enlargement free pennis pills sample natural penis enargement exercise penis enargement secret vigrx pic
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